This is an online lab notebook to document my research at the Institute of Marine at Coastal Sciences at Rutgers University. And by popular demand, a running log.
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- Name: alex
- Location: Rutgers University, New Jersey, United States
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Monday, February 21, 2005
Ernst, 2000
These notes and thoguhts arose form the reading of Ernst et al. [2000] Carbohydrates in Biochemistry and Biology.
Can polysialic acid (PSA) be used to test S.costatum as a physiological or morphological coagulator? PSA is used to for repulsive carbo-carbo interaction (pp1073). Repulsion is due to either pure ionic repulsion or due to physical hinderance as a result of the large hydration volume of thed polymer. Hyaluronon (HA) may also function in the same capacity as PSA.
Molecular interaction involving carbohydrates tend to be weak. Polyvalence is very important for carbohydrate-carbohydrate interactions. Beyond structural arrangements, carbohydrate-carbohydrate models of cellular interaction can be controlled by various means of polyvalence; surface density of presented structures, ionic strength for modulating attractive and repulsive forces, changes in biosynthesis of carbohydrate sequences.
- posted by alex @ 18:01
